Unlock the Editor’s Digest at no cost
Roula Khalaf, Editor of the FT, selects her favorite tales on this weekly e-newsletter.
Hedge fund Citadel has made a £305mn guess towards drugmaker GSK, the most important quick place towards the corporate in additional than a decade.
Billionaire Ken Griffin’s hedge fund disclosed that it had entered the online quick place on Tuesday, with the guess price 0.51 per cent of the corporate’s inventory, in keeping with knowledge from the Monetary Conduct Authority compiled by supplier Breakout Level.
The final time any agency disclosed a guess towards the FTSE 100 pharmaceutical group was in 2013, in keeping with the FCA disclosures.
GSK’s shares have risen 11 per cent within the final month, because the drugmaker raised its long-term gross sales forecast and launched into a rare £2bn stock buyback earlier this month. GSK reported higher than anticipated earnings on robust gross sales of HIV and most cancers medication.
However the inventory has lagged rival pharmaceutical firms, because the drugmaker has didn’t excite traders about its pipeline of latest medicines and vaccines, which it wants to switch its HIV medication after they face a patent cliff later within the decade. Prior to now 5 years, shares in GSK have fallen 15 per cent, in contrast with the S&P 500 pharmaceutical index, which rose 45 per cent.

Emma Walmsley, GSK’s chief govt, has already confronted a battle towards an activist investor, when hedge fund Elliott Administration constructed a multibillion-pound stake within the firm in 2021. Elliott questioned whether or not Walmsley was the precise chief for the corporate, given she doesn’t have a scientific background. It additionally pushed for GSK to contemplate takeover affords for its client well being enterprise Haleon, which was later spun off.
Analysts at JPMorgan stated the fourth-quarter earnings and the corporate’s steerage for 2025 have been “constructive”. However they added: “We imagine the market may query the logic of a buyback three years from the beginning of the HIV patent cliff, with a nonetheless pretty skinny late stage pipeline”. Analysts at Barclays additionally stated that the share buyback was “sudden” however analysts at Jefferies stated the transfer was “properly obtained”.
GSK’s shares collapsed in August 2022 when lawsuits over the heartburn drug Zantac emerged. However when GSK settled the overwhelming majority of circumstances for $2.2bn in October final yr, the shares didn’t return to their earlier stage.
The corporate has additionally suffered from sudden dangerous information for 2 key merchandise. In 2022, GSK withdrew its most cancers drug Blenrep from the US market, after a trial didn’t meet FDA necessities for medicines that had obtained an accelerated approval. After additional research, the corporate is now anticipating the drug will probably be reapproved by the regulator by July 2025.
Gross sales of Arexvy, its vaccine for the respiratory syncytial virus, generally known as RSV, dropped within the second half of final yr as a result of a US advisory panel unexpectedly advisable limiting its use.
Citadel is the world’s top-performing hedge fund in keeping with knowledge from LCH Investments, an investor in hedge funds. The agency homes lots of of buying and selling groups who guess on all kinds of belongings together with equities. Citadel manages $65bn price of investor capital as of the beginning of the yr, and was up 15.1 per cent in 2024.
Shares in GSK have been decrease by 0.5 per cent to 1,438p on the finish of Friday buying and selling in London.
Citadel declined to remark because the agency doesn’t talk about its positions. GSK declined to remark as a result of the corporate doesn’t talk about particular person shareholders.